Transfusion strategy for acute upper gastrointestinal bleeding

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Transfusion strategy for acute upper gastrointestinal bleeding.

Clinical question Does a hemoglobin transfusion threshold of 70 g/L yield better patient outcomes than a threshold of 90 g/L in patients with acute upper gastrointestinal bleeding? Article chosen Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013;368(1):11-21. Study objectives The authors of this study measured mortality, ...

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Transfusion strategies for acute upper gastrointestinal bleeding.

BACKGROUND The hemoglobin threshold for transfusion of red cells in patients with acute gastrointestinal bleeding is controversial. We compared the efficacy and safety of a restrictive transfusion strategy with those of a liberal transfusion strategy. METHODS We enrolled 921 patients with severe acute upper gastrointestinal bleeding and randomly assigned 461 of them to a restrictive strategy ...

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Recurrent bleeding in acute upper gastrointestinal hemorrhage: transfusion confusion.

OBJECTIVE Acute upper gastrointestinal (UGI) hemorrhage is a common, often serious condition encountered in the emergency department (ED). Previous research has suggested that transfusion of blood products may interfere with the hypercoagulable state induced by significant blood loss. Our objective was to determine whether the frequency of rebleeding is higher in patients with UGI bleeding who ...

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Blood transfusion for upper gastrointestinal bleeding: is less more again?

BACKGROUND The hemoglobin threshold for transfusion of red blood cells in patients with acute gastrointestinal (GI) bleeding is controversial. We compared the efficacy and safety of a restrictive transfusion strategy with those of a liberal transfusion strategy. METHODS OBJECTIVE The objective was to prove that the restrictive threshold for red blood cell transfusion in patients with acute...

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The management of acute upper gastrointestinal bleeding.

Acute upper gastrointestinal (GI) bleeding is one of the most common medical emergencies and most cases require urgent medical assessment. Half of all cases are due to peptic ulcer and this article focuses on non-variceal bleeding. The priority, following emergency hospital admission, is to support the circulation of the shocked patient rather than to identify the source of bleeding. After resu...

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ژورنال

عنوان ژورنال: CJEM

سال: 2015

ISSN: 1481-8035,1481-8043

DOI: 10.1017/cem.2014.76